Introduction: Importance of resolving tumor cell diversity for precision oncology. Single‑Cell Sequencing Overview: Techniques, benefits, and challenges. Spatial Transcriptomics: Adding tissue context—mapping cancer microenvironment. Dr. Kwatra’s Research: Summarize his labs’ findings, e.g., insights on tumor heterogeneity or immune infiltration. Clinical Utility: Identifying new drug targets, predicting resistance, optimizing therapy. Future Directions: Where the field is […]
Introduction: Explain the challenge of reproducible NGS and single-cell pipelines. Workflow Tools: Overview of Snakemake & Nextflow, emphasizing ease of integration with cloud/clinical settings. Dr. Kwatra’s Pipeline: Share insights into his scalable workflows for multi-omics and clinical decision support. Technical Highlights: Data staging, containerization, benchmarking, error handling. Open Source & Collaboration: Encourage readers to explore […]
Introduction: Define computational oncology and its promise in cancer treatment. AI & Genomics Integration: Discuss how AI analyzes big genomic datasets—cfDNA, liquid biopsies—to uncover tumor mutations. Case Study: Highlight a specific application, e.g., predictive modeling for immunotherapy response. Clinical Impact: Show how this translates to personalized treatment plans and improved outcomes. Future Outlook: Emerging trends—multi‑omics […]